I joined the Princess Máxima Center as a basic researcher and pediatrician in training in June 2018. My primary research interest lies in understanding the molecular biology of pediatric soft tissue sarcomas (STS) and to use that knowledge to develop new treatment options for patients suffering from these tumors. To this end, I study establishment procedures for novel preclinical models of pediatrist STS (i.e., tumor organoid models) as well as bulk and single-cell genomics of these tumors. I am furthermore member of the molecular tumor board of the Dutch iTHER as well as the German INFORM pediatric precision medicine trial.
My hobbies include sports (running, bootcamp) and gaming (board games, tabletop role-playing games, video games). I am the proud father of a boy and a girl.
Siem Jongsma
Bioinformatician
Hi! My name is Siem and I joined the Drost group as a bioinformatician in June 2025. During my Master’s I worked on projects involving whole genome sequencing data from cancer patients. In the Drost group, I will work on the analysis of single cell data, including RNAseq, ATACseq, multiome analysis and spatial transcriptomics. I am excited to explore these techniques and use them to investigate the role of cancer cell plasticity.
In my free time, I like to meet up and play games with friends, listen to music and go to concerts, read a book, plan my next vacation and I like to try out photography.