I joined the Princess Máxima Center as a basic researcher and pediatrician in training in June 2018. My primary research interest lies in understanding the molecular biology of pediatric soft tissue sarcomas (STS) and to use that knowledge to develop new treatment options for patients suffering from these tumors. To this end, I study establishment procedures for novel preclinical models of pediatrist STS (i.e., tumor organoid models) as well as bulk and single-cell genomics of these tumors. I am furthermore member of the molecular tumor board of the Dutch iTHER as well as the German INFORM pediatric precision medicine trial.
My hobbies include sports (running, bootcamp) and gaming (board games, tabletop role-playing games, video games). I am the proud father of a boy and a girl.
Paula Ruiz Duran
PhD student
Hi! I’m Paula, a shared PhD student in the research groups of Jarno Drost (Princess Máxima Center) and Elzo de Wit (Netherlands Cancer Institute) since March 2025. My research focuses on the epigenetic transformations driving Malignant Rhabdoid Tumors. Working alongside a computational PhD student, we will use patient-derived organoids, state-of-the-art protein degradation tools, and advanced epigenetic analysis to explore novel therapeutic strategies targeting epigenetic reprogramming.
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Outside the lab, I enjoy staying active, whether it’s hiking, dancing, or spending time with friends and family. I love game nights, dining out, and traveling. Recently, I’ve also taken up crocheting as a new hobby!