I joined the Princess Máxima Center as a basic researcher and pediatrician in training in June 2018. My primary research interest lies in understanding the molecular biology of pediatric soft tissue sarcomas (STS) and to use that knowledge to develop new treatment options for patients suffering from these tumors. To this end, I study establishment procedures for novel preclinical models of pediatrist STS (i.e., tumor organoid models) as well as bulk and single-cell genomics of these tumors. I am furthermore member of the molecular tumor board of the Dutch iTHER as well as the German INFORM pediatric precision medicine trial.
My hobbies include sports (running, bootcamp) and gaming (board games, tabletop role-playing games, video games). I am the proud father of a boy and a girl.
Mariël Brok
Research technician
I’m Mariel Brok. I’ve been involved (since October 2015) in setting up a workable laboratory environment for researchers in the Maxima, first at the Hubrecht Institute and from May 2018 onwards in this beautiful building as part of my head technician role.
Besides that, I recently joined the Drost group, working as a senior research technician on several projects focusing on RMS tumors. This means a lot of cell culture, transductions, cloning, histology, RNA-scope, and other molecular techniques in order to investigate new potential druggable targets or pathways. This will, hopefully, further improve the treatment and ultimately increase the survival rate of the children that suffer from this type of cancer.
In my spare time I like to play tennis, sing and do some painting and crafts. I also enjoy taking city trips or hikes with family or friends.