I joined the Princess Máxima Center as a basic researcher and pediatrician in training in June 2018. My primary research interest lies in understanding the molecular biology of pediatric soft tissue sarcomas (STS) and to use that knowledge to develop new treatment options for patients suffering from these tumors. To this end, I study establishment procedures for novel preclinical models of pediatrist STS (i.e., tumor organoid models) as well as bulk and single-cell genomics of these tumors. I am furthermore member of the molecular tumor board of the Dutch iTHER as well as the German INFORM pediatric precision medicine trial.
My hobbies include sports (running, bootcamp) and gaming (board games, tabletop role-playing games, video games). I am the proud father of a boy and a girl.
My Name is Jiayou He and am currently a PhD student in the Drost lab. After finishing my Bachelor and Master education at Free University Berlin, I decided to start my PhD at Prinses Máxima Center and am also part of the VAGABOND consortium (https://vagabondnetwork.com). My projects are mainly focusing on identifying subtype-specific epigenetic driver events in Atypical teratoid rhabdoid tumors (ATRTs) using patient-derived organoid models. At the same time, I am also working on a 10X Multiome project with the aim to decipher inter- and intra-tumor heterogeneity in Malignant Rhabdoid Tumors (MRTs). In my free time, I like traveling around and going to dance classes as well as learning different languages.