I joined the Princess Máxima Center as a basic researcher and pediatrician in training in June 2018. My primary research interest lies in understanding the molecular biology of pediatric soft tissue sarcomas (STS) and to use that knowledge to develop new treatment options for patients suffering from these tumors. To this end, I study establishment procedures for novel preclinical models of pediatrist STS (i.e., tumor organoid models) as well as bulk and single-cell genomics of these tumors. I am furthermore member of the molecular tumor board of the Dutch iTHER as well as the German INFORM pediatric precision medicine trial.
My hobbies include sports (running, bootcamp) and gaming (board games, tabletop role-playing games, video games). I am the proud father of a boy and a girl.

Giorgio Mazzarese
Master student
I am a Cancer, Stem cells and Developmental biology masters’ student at Utrecht University, and I started a one-year internship in the Drost lab in October 2026. Together with Charlotte, I will investigate the role of Lgr5+ cells in different subtypes of atypical teratoid/rhabdoid tumors (AT/RTs).
I am eager to conduct this project because it will allow me to further develop my scientific expertises by learning state-of-art research techniques, including genetic manipulations and multi-omic approaches in organoid models. At the same time, I look forward to developing my professional skills by collaborating with and learning from the entire group.
When I am not in the lab, you can find me mixing electronic musing and doing DJ sets. I also love food, so you will often find me cooking Italian dishes or, as I like to say, doing experiments in the kitchen. In my spare time, I also enjoy hanging out with friends and going on road trips in Europe.
